The global health impact of antimicrobial resistance in animal populations veterinaryrelated factors influencing the global spread of amr national and international amr programs references and resources summary animated. The whos report was quite comprehensive and wellbalanced. Antimicrobial resistance global report on surveillance 2014 1. International infectious disease surveillance has been conducted by the united states u. This who report, produced in collaboration with member states and other partners, provides as accurate a picture as is presently possible of the magnitude of amr and the current state of surveillance globally. Annual surveillance reports on antimicrobial resistance. Surveillance and monitoring of antimicrobial resistance amr steven solomon top, division of healthcare quality promotion and kashef ijaz bottom, division of global health protection, centers for disease control and prevention, atlanta, ga, usa antibiotic resistance is a global problem of increasing significance that takes a costly toll. Cddep maps dangerous trends in antibiotic resistance on a. The first data from the world health organization global antimicrobial surveillance system glass have reported high rates of resistance to antibiotics commonly used to treat serious bacterial infections in many countries across the world. As who, along with partners across many sectors moves ahead in developing a global action plan to mitigate amr, this report will serve as a. Public health implications of antimicrobial resistance surveillance d.
In its first global evaluation of surveillance and information on antimicrobial resistance, the world health organization who called attention to increasing levels of bacterial resistance to many common drugs. Whereas consumption decreased in countries such as mexico or chile, it sharply increased in many lowincome and middleincome countries lmic. Who global surveillance report on antimicrobial resistance. Terrestrial animal health standards commission report february 2017 chapter 6. Surveillance report, external quality assessment 30 jan 2017. The first world health organization who global report on surveillance of amr, published in april 2014, collected for the first time data from national and international surveillance networks, showing the extent of this phenomenon in many parts of the world and also the presence of large. Antimicrobial resistance global report on surveillance 2014 x summary antimicrobial resistance amr threatens the e. Antimicrobial resistance amr is a serious threat to global public health. Global antimicrobial resistance surveillance system manual 2016. Who advisory group on integrated surveillance of antimicrobial resistance. Antimicrobial resistance surveillance not every isolate was tested for resistance to every antibiotic included in this report.
Surveillance of antibiotic resistance at national level a number of early who meetings recommended the establishment of local, national, and regionalglobal surveillance programs who, 1981, 1982, 1994. Who report on global antibiotic resistance highlights. Surveillance is conducted to determine the extent and pattern of resistance amongst the most important pathogens causing infections in humans. When calculating percent susceptibility to an antibiotic, the denominator is the number of cases tested for that particular antibiotic. First who antimicrobial surveillance data reveal high. Types of surveillance data and meaningful indicators for. Antimicrobial resistance amr threatens the effective prevention and treatment of an everincreasing range of infections caused by bacteria, parasites, viruses and fungi.
Global report on surveillance world health organization on. Wells global response to amr and the value of vaccines table 1 summary of. First who antimicrobial surveillance data reveal high levels of resistance globally susan mayor london the first data from the world health organization global antimicrobial surveillance system glass have reported high rates of resistance to antibiotics commonly used to treat serious bacterial infections in many countries across the world. Pdf on may 31, 2014, p ravi shankar and others published antimicrobial resistance. Moreover, when surveillance programs are being developed, they should be designed to be useful, meaning that they should contribute to the prevention and control of antimicrobial resistance. Amr is not simply a problem of medical science being beaten by nature. Antibacterial resistance has a negative effect on patient outcomes and health expenditures 3. Antimicrobial resistance is an increasingly serious health issue in ontario and worldwide.
Global report on surveillance 2014 focused on seven bacteria of international concern causing common infections 95 bacterial agent finding implication. Antimicrobial resistance amr is a complex issue of global concern. In response to the increasing emergence of antimicrobial resistance amr as a global health threat, in may 2017 the canadian institutes of health researchs cihr institutes of infection and immunity and population and public health launched a funding opportunity for research projects to. Total number of invasive isolates tested n and percentage with resistance to meticillin mrsa including 95% confidence intervals 95% ci, eueea countries, 20122015. Another important finding of the report is that surveillance of antibacterial resistance is neither coordinated nor harmonized and there are many gaps in information on bacteria of major public health importance.
A global programme for amr surveillance with the objectives to foster national amr surveillance systems and harmonize global standards estimate the extent and burden of amr globally by selected indicators analyse and report global data on a regular basis detect emerging resistance and its international spread. Canadian institutes of health research backgrounder. Harmonisation of national antimicrobial resistance surveillance and monitoring programmes article 6. As more antimicrobial drugs become ineffective and fail to treat a growing number of infections, those infections persist and increase the risk of disease, poor health and.
Surveillance of antimicrobial resistance is needed to monitor trends and magnitude of the problem, to inform treatment guidelines and other activities for resistance containment and to assess impact of interventions to control amr. Trends in antibiotic resistance and their consequences for health, welfare and the economy are rapidly changing ecdc, 2010a. This includes activities that monitor the presence of antimicrobial. This accelerating problem accounts for substantial number of excess deaths, especially among infants. The first who global report on antimicrobial resistance from 2014 showed that there is a need to. Antimicrobial resistance surveillance in the afhscgeis. Health and economic impacts of antimicrobial resistance in thailand. The global response to the threat of antimicrobial. Antimicrobial drug resistance is usually not monitored in underresourced countries because they lack surveillance networks, laboratory capacity, and appropriate diagnostics. Report authors say antibiotic stewardship is the key component of that action, and they challenge the frequentlycited notion that the problem with antibiotic resistance is a lack of new drugs in. Antimicrobial resistance surveillance in europe 2016. Reynold bergen, bcrc science director, originally appeared in the june 2014 issue of canadian cattlemen magazine and is reprinted on the bcrc blog with permission of the publisher the world health organizations antimicrobial resistance. Iv who library cataloguinginpublication data antimicrobial resistance.
Cdc global health infographics antibiotic resistance. Surveillance for antimicrobial drug resistance in under. Surveillance for antimicrobial resistance in croatia. It also shows the gaps in surveillance systems and the. Summary report published as technical document with reference number. Antibiotic resistance threatens the success of medical interventions at all levels of health care and creates a set of specific challenges for clinical, therapeutic and public health interventions with local, national, and global dimensions. Antimicrobial resistance surveillance in europe 2015. Antimicrobial resistance amr is a key public health concern that threatens effective treatment of severe infections, both locally and globally. Department of defense dod for many years and has been consolidated within the armed forces health surveillance center, division of global emerging infections surveillance and response system afhscgeis since 1998. This report examines, for the first time, the current status of surveillance and information on amr, in particular antibacterial resistance abr, at country level worldwide.
A postantibiotic era in which common infections and minor. Surveillance including developing laboratory capacity and the development of a longterm strategy to collect and report high quality data in a systematic fashion. Global antimicrobial resistance surveillance system 1. Surveillance of antimicrobial resistance for local and. To do that, microbiologists will have to collect not only laboratory data but the clinical data that is so often missing from surveillance reports. Veterinary antimicrobial resistance and sales surveillance. They will meet again this month to finalize first drafts of. December 2014 report of the ad hoc group on antimicrobial resistance attached to the february 2015 report of the scientific commission chapter 6. The report is the first from the whos global antimicrobial surveillance system or glass launched in 2015 to support, build and benefit from efforts to track resistance medicines used to treat community and hospital infections currently in 52 countries across the economic spectrum. The report, the state of the worlds antibiotics, 2015, lays out six strategies that belong in every national plan to halt the spread of resistance. Strengthening global amr surveillance is critical as it is the basis for informing global strategies, monitoring the effectiveness of public health interventions and detecting new trends and threats. Serious infections caused by multidrug and pandrug resistant bacteria in the face of dry pipeline of new. Infections particularly affected by antimicrobial drug resistance include tuberculosis, malaria, severe acute. Global antimicrobial resistance surveillance system.
Antimicrobial resistance global report on surveillance 2014 x summary antimicrobial resistance amr threatens the effective prevention and treatment of an everincreasing range of infections caused by bacteria, parasites, viruses and fungi. Sahm, phd vp global microbiology services chief scientific officer. Surveillance report, external quality assessment 15 nov 2017. Guidelines for surveillance of drug resistance in tuberculosis 5th edition 2015. High proportions of resistance were reported in all regions to common treatments for bacteria causing infections in both healthcare settings and in the community 2. The misuse of antibiotics in the medical, veterinary. Strengthening global amr surveillance is critical as it is the basis. Antimicrobial resistance amr is one of the most serious global public health threats in this century. Antimicrobial resistance ar is a growing public health threat of broad concern to countries and multiple sectors.
In 2015, who launched the global antimicrobial resistance surveillance system glass in order to standardize the collection of data on amr in member states, for planning, prevention and intervention programmes. Antimicrobial resistance global report on surveillance 2014. Uk veterinary antibiotic resistance and sales surveillance 2015 ref. In november 2008, expert working groups were formed.
An increasing number of governments around the world are devoting efforts to a problem so serious that it threatens the achievements of modern medicine. A framework for global surveillance of antibiotic resistance. The findings document resistance to antibiotics, especially socalled last resort antibiotics, in all regions of the world. In addition, this report aims to provide guidance and inspiration to countries that are building or strengthening their national antimicrobial resistance surveillance and stimulate the sharing of.
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